A relative has one of the newer Merc 4.5 liter V6s with that quick drain system, we used it last fall and it seemed to drain a lot of water so thinking it was fine, then I manually filled with AF. And it was fine no problems in the spring.
My thought for this year is to collect what drains from the engine starting with a dry bilge, if it comes close to filling a 5 gallon bucket then it still drained. I know it takes about 4.5 gallons to totally fill my 4.3, and that Merc 4.5 is just an updated 4.3. That engine compartment is so damn cramped I can't fit myself down in there, if there was a problem. Really prefer my old engine with manual drains and METAL drain plugs!