I have a custom boat, with a custom built 350. Long block is a new gm Goodwrench pre 85 350 has Volvo Penta manifolds, Edelbrock 4 brrl. 750 cfm DUI ignition bolted to a mercuismer out drive. Runs good but I want more. My auluminum prop now has a nick. It's a 19p full throttle with the 4 brrl pumping I get about 4400 rpm , struggles a little to get on plane gotta force ii with trim. Struggles real bad at the highh altutude lakes (hangs up at 2200 rpm i wonder what max rpm for my engine is? I also wonder if a cam would help, I wanna get a stainless steel prop but only once....
as for your "custom" franken motor how was the motor built? who built it? what went into it specifically?
my guess there is nothing, and I repeat nothing special about your motor other than the carb is too big for the application (750 cfm would be for a BBC in a boat or a high RPM 383 stroker spinning about 6000 RPM)
if you are only able to spin a 19p prop at 4400 RPM most likely its just a stock pre1985 generic truck motor with flat-top pistons with 4 valve notches in each piston. that combination would produce about 260hp at the flywheel.
if that is the case, then you're simply running out of motor. the hickup at 2200 is most likely too big a carb for the motor you have, especially at high altitude lakes. you may want to consider dropping down to a 600 cfm carb and re-jetting.
now if the motor was built with vortec heads, proper LCQ style pistons, a dual plane intake with a 2" phenolic spacer. you could build some torque, and be spinning a 23p prop at 5000 RPM
FWIW....a stock late 80s volvo penta SBC (stock 9.4:1 compression, included crate motor hi-po 64cc heads that were part of VPs mix from GM, a cast-iron intake with a 715CFM holley) will turn two props at about 4600 while producing 271hp at the props.