After you drain and poke all the holes (1 on each side of the block 1 for each manifold plus any p/s or any other coolers that need to be drained)... re-connect the bottom end of the big hose that connects the thermostat housing with the front circulation pump (you should have disconnected the bottom end of this to drain). Now disconnect the top end at the thermostat housing and start filling it with no tox AF till it comes out the thermostat housing neck. Reconnect hose engine is filled no need to remove thermostat. For the exhaust manifolds after draining and poking replace the plugs and disconnect t the water feed hoses at the thermostat housing and fill each manifold till it runs out the exhaust. Then reconnect those hoses. Finally put the drive down and disconnect the raw water hose from the transom mount at the thermostat housing. Point it down to drain then hold it up and put a funnel in it; fill it with AF till it runs out the drive water intakes. PS I use either -100 or a 50/50 mix of Sierra no tox AF. Both stay liquid to the lowest temps we ever get (zero to a bit below), the -50 and -60 get hard at higher temps then that. The Sierra is cheaper than the -100 by about 5 bucks per gallon.