Ok, but, it's a closed loop sytem and that requires an O2 sensor in the exhaust manifold. Technicaly you can run without one, but you are buying a lot of electronics that will never be used and is not as efficent. You can almost think of running like that as being the equivilent to "limp home" mode on most cars. Yes it will work, no you really get nothing from it.
Yes you can buy new manifolds set up for that but thery are NOT cheap. I see they offer a heated O2 sensor (marine exhausts don't get hot enough to work without being heated) "kit" to install the sensor in existing risers but I've not tried or even seen one installed so I can't comment. Also note the throttle body faces forward, is your engine bay able to accomodate it and a spark arrestor? (You'll probably go with a KN filter or something along the same design.) Figure its going to add 6" to 8" length to the throtle body, make certain it'll fit in your boat.
Price of this fella is $2,100, plus $275 for the O2 setup and I'd say you'll have $2,500 (minimum) in it pretty easily by the time its running. Ask yourself, are you going to get $2500 worth of performance and economy from it? If the answer is no, ask why you are doing it then.
In my part of the world I can pick up a 383 stroker for that sort of money if I want ponies.
http://kansascity.craigslist.org/pts/2814171320.html